Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies

Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies

Abstract We aimed to develop a sandwich ELISA to detect prostate-specific membrane antigen (PSMA) on small extracellular vesicles (EVs) using T-cell immunoglobulin domain and mucin domain-containing protein 4 (Tim4) as a capture molecule for EVs and to evaluate its diagnostic potential in urologic m...

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Bibliographic Details
Main Authors: Kyojiro Kawakami, Yasunori Fujita, Taku Kato, Kengo Horie, Takuya Koie, Keitaro Umezawa, Hiroki Tsumoto, Yuri Miura, Yasuo Katagiri, Tatsuhiko Miyazaki, Ikuroh Ohsawa, Kosuke Mizutani, Masafumi Ito
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94603-9

Internet

https://doi.org/10.1038/s41598-021-94603-9

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