c21orf59/kurly Controls Both Cilia Motility and Polarization

c21orf59/kurly Controls Both Cilia Motility and Polarization

Cilia are microtubule-based projections that function in the movement of extracellular fluid. This requires cilia to be: (1) motile and driven by dynein complexes and (2) correctly polarized on the surface of cells, which requires planar cell polarity (PCP). Few factors that regulate both processes...

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Bibliographic Details
Main Authors: Kimberly M. Jaffe, Daniel T. Grimes, Jodi Schottenfeld-Roames, Michael E. Werner, Tse-Shuen J. Ku, Sun K. Kim, Jose L. Pelliccia, Nicholas F.C. Morante, Brian J. Mitchell, Rebecca D. Burdine
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Subjects:
Kurly (Kur)
c21orf59
cilia
planar cell polarity
disheveled
ciliopathy
primary ciliary dyskinesia
multiciliated cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716300626

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http://www.sciencedirect.com/science/article/pii/S2211124716300626

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