Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA.

Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA.

Rift Valley fever virus (RVFV), a member of the genus Phlebovirus within the family Bunyaviridae, is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, while in livestock it causes fever and high abo...

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Bibliographic Details
Main Authors: John C Morrill, Tetsuro Ikegami, Naoko Yoshikawa-Iwata, Nandadeva Lokugamage, Sungyong Won, Kaori Terasaki, Aya Zamoto-Niikura, C J Peters, Shinji Makino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2848673?pdf=render

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http://europepmc.org/articles/PMC2848673?pdf=render

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