Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.

This study was designed to explore the therapeutic potential of suppressing MAP kinase and PI3K/Akt pathways and histone deacetylase (HDAC) to induce the expression of sodium/iodide symporter (NIS) and radioiodine uptake in non-thyroid cancer cells.We tested the effects of the MEK inhibitor RDEA119,...

Full description

Bibliographic Details
Main Authors: Zhi Liu, Mingzhao Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281006?pdf=render