HCMV Infection of Human Trophoblast Progenitor Cells of the Placenta Is Neutralized by a Human Monoclonal Antibody to Glycoprotein B and Not by Antibodies to the Pentamer Complex

HCMV Infection of Human Trophoblast Progenitor Cells of the Placenta Is Neutralized by a Human Monoclonal Antibody to Glycoprotein B and Not by Antibodies to the Pentamer Complex

Human cytomegalovirus (HCMV) is the major viral cause of congenital infection and birth defects. Primary maternal infection often results in virus transmission, and symptomatic babies can have permanent neurological deficiencies and deafness. Congenital infection can also lead to intrauterine growth...

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Bibliographic Details
Main Authors: Martin Zydek, Matthew Petitt, June Fang-Hoover, Barbara Adler, Lawrence M. Kauvar, Lenore Pereira, Takako Tabata
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Viruses
Subjects:
HCMV
congenital
trophoblast
progenitors
neutralizing
placenta
development
neutralization
pentamer
hyperimmune globulin
Online Access:http://www.mdpi.com/1999-4915/6/3/1346

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http://www.mdpi.com/1999-4915/6/3/1346

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