Hibernating bear serum hinders osteoclastogenesis in-vitro.

Bears do not suffer from osteoporosis during hibernation, which is associated with long-term inactivity, lack of food intake, and cold exposure. However, the mechanisms involved in bone loss prevention have scarcely been elucidated in bears. We investigated the effect of serum from hibernating Japan...

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Bibliographic Details
Main Authors: Alireza Nasoori, Yuko Okamatsu-Ogura, Michito Shimozuru, Mariko Sashika, Toshio Tsubota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238132