Pharmacological and Molecular Evidence of Neuroprotective Curcumin Effects Against Biochemical and Behavioral Sequels Caused by Methamphetamine: Possible Function of CREB-BDNF Signaling Pathway

Pharmacological and Molecular Evidence of Neuroprotective Curcumin Effects Against Biochemical and Behavioral Sequels Caused by Methamphetamine: Possible Function of CREB-BDNF Signaling Pathway

Introduction: The neuroprotective impact of curcumin and the role of CREB (Cyclic AMP Response Element Binding protein)-BDNF (Brain-Derived Neurotrophic Factor) signaling pathway was evaluated in Methamphetamine (METH)-induced neurodegeneration in rats. Methods: Sixty adult male rats were randomly d...

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Bibliographic Details
Main Authors: Mina Gholami, Farzad Hozuri, Setayesh Abdolkarimi, Mahsa Mahmoudi, Majid Motaghinejad, Sepideh Safari, Samira Sadr
Format: Article
Language:English
Published: Iran University of Medical Sciences 2021-05-01
Series:Basic and Clinical Neuroscience
Subjects:
methamphetamine
curcumin
neurodegeneration
cyclic amp response element binding protein
brain-derived neurotrophic factor
Online Access:http://bcn.iums.ac.ir/article-1-1382-en.html

Internet

http://bcn.iums.ac.ir/article-1-1382-en.html

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