Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure

Unclassified four-repeat tauopathy associated with familial parkinsonism and progressive respiratory failure

Abstract We describe an autopsied patient with familial parkinsonism and unclassified four repeat-tau (4R-tau) aggregation. She presented with bradykinesia, truncal dystonia, and mild amnesia at the age of 61 and then exhibited body weight loss (15 kg over 8 months), sleep disturbances, and progress...

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Bibliographic Details
Main Authors: Masayoshi Nakano, Yuichi Riku, Kenya Nishioka, Masato Hasegawa, Yukihiko Washimi, Yutaka Arahata, Akinori Takeda, Kentaro Horibe, Akiko Yamaoka, Keisuke Suzuki, Masashi Tsujimoto, Yuanzhe Li, Hiroyo Yoshino, Nobutaka Hattori, Akio Akagi, Hiroaki Miyahara, Yasushi Iwasaki, Mari Yoshida
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Acta Neuropathologica Communications
Subjects:
Four-repeat tau aggregation
Familial parkinsonism
Respiratory failure
Autopsy
Postmortem study
Online Access:http://link.springer.com/article/10.1186/s40478-020-01025-1

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http://link.springer.com/article/10.1186/s40478-020-01025-1

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