2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes
Context: 2,3-Butanedione monoxime (BDM), an uncoupler of cardiac contraction, is commonly used in enzymatic dissociations to prevent hypercontraction of cardiomyocytes and in cardioplegic solutions to decrease oxygen demand during surgery. However, BDM affects multiple cellular systems including the...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA)
2016-12-01
|
Series: | Journal of Pharmacy & Pharmacognosy Research |
Subjects: | |
Online Access: | http://jppres.com/jppres/pdf/vol4/jppres16.150_4.6.206.pdf |