Podocentric view of glomerular proteinuria: Focused on cytoskeletal changes and toward promising targeted therapies and challenges

Podocentric view of glomerular proteinuria: Focused on cytoskeletal changes and toward promising targeted therapies and challenges

Abstract Among renal cells, podocytes (glomerular epithelial cells) are the most critical to prevent plasma proteins from excessive loss by forming their sophisticated foot processes (FP) and slit diaphragms (SD). A general finding in the glomeruli of patients with nephrotic syndrome is the foot pro...

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Bibliographic Details
Main Authors: Mei‐Chuan Kuo, Peir‐In Liang, Jer‐Ming Chang
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
actin cytoskeleton
foot processes
podocytes
proteinuria
Online Access:https://doi.org/10.1002/kjm2.12385

Internet

https://doi.org/10.1002/kjm2.12385

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