Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection.

Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite, Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global insights into the T. cruzi infective process, transcriptome dynamics were simultaneously captured in the parasite and ho...

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Main Authors: Yuan Li, Sheena Shah-Simpson, Kwame Okrah, A Trey Belew, Jungmin Choi, Kacey L Caradonna, Prasad Padmanabhan, David M Ndegwa, M Ramzi Temanni, Héctor Corrada Bravo, Najib M El-Sayed, Barbara A Burleigh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4821583?pdf=render