A Case of Methotrexate Neurotoxicity Presented as Status Epilepticus, Encephalopathy, and High Fever

High-dose methotrexate is used to treat a range of adult and childhood cancers including osteosarcoma. Significant neurotoxicity is reported in 1% to 4.5% of patients treated with high-dose methotrexate and can present in a wide variety of symptoms. We present a case of a 14-year-old boy with a rece...

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Bibliographic Details
Main Authors: Itay Ayalon MD, Shirley Friedman MD, Yoav Binenbaum MD, Noga Oppenheimer MD, Shelly Shiran MD, Galia Grisaru-Soen MD, Shimrit Uliel-Sibony MD, Miguel Glatstein MD, Jennifer Melissa Kaplan MD, MS, Efraim Sadot MD
Format: Article
Language:English
Published: SAGE Publishing 2019-07-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709619862311