Design of epidermal growth factor immobilization on 3D biocompatible scaffolds to promote tissue repair and regeneration

Abstract Exogenous application of human epidermal growth factor (hEGF) stimulates epidermal wound healing. The aim of this study was to develop bioconjugates based on hEGF mimicking the protein in its native state and thus suitable for tissue engineering applications, in particular for treating skin...

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Bibliographic Details
Main Authors: Teodora Bavaro, Sara Tengattini, Refaya Rezwan, Enrica Chiesa, Caterina Temporini, Rossella Dorati, Gabriella Massolini, Bice Conti, Daniela Ubiali, Marco Terreni
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81905-1