Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling

Cancer immunosurveillance is critical for the elimination of neoplastic cells. In addition, recent advances in immunological checkpoint blockade drugs have revealed the importance of the immune system in cancer treatment. As a component of the immune system, CD8+ T cells have important roles in supp...

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Bibliographic Details
Main Authors: Shin-ichi Tsukumo, Koji Yasutomo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00101/full