Lead Poisoning Disturbs Oligodendrocytes Differentiation Involved in Decreased Expression of NCX3 Inducing Intracellular Calcium Overload

Lead Poisoning Disturbs Oligodendrocytes Differentiation Involved in Decreased Expression of NCX3 Inducing Intracellular Calcium Overload

Lead (Pb) poisoning has always been a serious health concern, as it permanently damages the central nervous system. Chronic Pb accumulation in the human body disturbs oligodendrocytes (OLs) differentiation, resulting in dysmyelination, but the molecular mechanism remains unknown. In this study, Pb a...

Full description

Bibliographic Details
Main Authors: Teng Ma, Xiyan Wu, Qiyan Cai, Yun Wang, Lan Xiao, Yanping Tian, Hongli Li
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:International Journal of Molecular Sciences
Subjects:
Pb exposure
oligodendrocytes
differentiation
sodium/calcium exchanger 3
calcium signal
Online Access:http://www.mdpi.com/1422-0067/16/8/19096

Internet

http://www.mdpi.com/1422-0067/16/8/19096

Similar Items