Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing.

Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing.

Although vaccines are important in preventing viral infections by inducing neutralizing antibodies (nAbs), HIV-1 has proven to be a difficult target and escapes humoral immunity through various mechanisms. We sought to test whether HIV-1 Env mimics may serve as immunogens.Using random peptide phage...

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Bibliographic Details
Main Authors: Michael Humbert, Robert A Rasmussen, Helena Ong, Fabian M P Kaiser, Shiu-Lok Hu, Ruth M Ruprecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2597739?pdf=render

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