Identification of mimotopes with diagnostic potential for Trypanosoma brucei gambiense variant surface glycoproteins using human antibody fractions.

by Liesbeth Van Nieuwenhove, Philippe Büscher, Fatima Balharbi, Michael Humbert, Tessa Dieltjens, Yves Guisez, Veerle Lejon
Published 2012-01-01

Inducing cross-clade neutralizing antibodies against HIV-1 by immunofocusing.

by Michael Humbert, Robert A Rasmussen, Helena Ong, Fabian M P Kaiser, Shiu-Lok Hu, Ruth M Ruprecht
Published 2008-01-01

Isolation of monoclonal antibodies with predetermined conformational epitope specificity.

by Anton M Sholukh, Muhammad M Mukhtar, Michael Humbert, Sosthène S Essono, Jennifer D Watkins, Hemant K Vyas, Vivekanandan Shanmuganathan, Girish Hemashettar, Maria Kahn, Shiu-Lok Hu, David C Montefiori, Victoria R Polonis, Peter H Schur, Ruth M Ruprecht
Published 2012-01-01

An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV.

by Jennifer D Watkins, Nagadenahalli B Siddappa, Samir K Lakhashe, Michael Humbert, Anton Sholukh, Girish Hemashettar, Yin Ling Wong, John K Yoon, Wendy Wang, Francis J Novembre, Francois Villinger, Chris Ibegbu, Kalpana Patel, Davide Corti, Gloria Agatic, Fabrizia Vanzetta, Siro Bianchi, Jonathan L Heeney, Federica Sallusto, Antonio Lanzavecchia, Ruth M Ruprecht
Published 2011-03-01