Combined association of Presenilin-1 and Apolipoprotein E polymorphisms with maternal meiosis II error in Down syndrome births

Combined association of Presenilin-1 and Apolipoprotein E polymorphisms with maternal meiosis II error in Down syndrome births

Abstract Alzheimer's disease and Down syndrome often exhibit close association and predictively share common genetic risk-factors. Presenilin-1 (PSEN-1) and Apolipoprotein E (APOE) genes are associated with early and late onset of Alzheimer's disease, respectively. Presenilin −1 is involve...

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Bibliographic Details
Main Authors: Pranami Bhaumik, Priyanka Ghosh, Sujay Ghosh, Eleanor Feingold, Umut Ozbek, Biswanath Sarkar, Subrata Kumar Dey
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2017-07-01
Series:Genetics and Molecular Biology
Subjects:
Chromosome
genetic polymorphism
karyotype
meiosis
microsatellite markers
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400577&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400577&lng=en&tlng=en

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