Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils

Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils

Fucoidan, a natural sulfated polysaccharide, displays various biological activities including antioxidant properties. We examined the neuroprotective effect of fucoidan against transient global cerebral ischemia (tGCI) in high-fat diet (HFD)-induced obese gerbils and its related mechanisms. Gerbils...

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Bibliographic Details
Main Authors: Ji Hyeon Ahn, Myoung Cheol Shin, Dae Won Kim, Hyunjung Kim, Minah Song, Tae-Kyeong Lee, Jae-Chul Lee, Hyeyoung Kim, Jun Hwi Cho, Young-Myeong Kim, Jong-Dai Kim, Soo Young Choi, Moo-Ho Won, Joon Ha Park
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
obesity
transient global cerebral ischemia
fucoidan
neuroprotection
oxidative stress
antioxidant enzymes
Online Access:https://www.mdpi.com/1422-0067/20/3/554

Internet

https://www.mdpi.com/1422-0067/20/3/554

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