Ring synthetic chromosome V SCRaMbLE

Genome structural variation can play an important functional role in phenotypic diversity. Here the authors use the SCRaMbLE system on a ring synthetic chromosome V to generate complex rearrangements distinct from a rearranged linear chromosome.

Bibliographic Details
Main Authors: Juan Wang, Ze-Xiong Xie, Yuan Ma, Xiang-Rong Chen, Yao-Qing Huang, Bo He, Bin Jia, Bing-Zhi Li, Ying-Jin Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06216-y