Genetic variation within the Mx gene of commercially selected chicken lines reveals multiple haplotypes, recombination and a protein under selection pressure.

The Mx protein is one of the best-characterized interferon-stimulated antiviral mediators. Mx homologs have been identified in most vertebrates examined; however, their location within the cell, their level of activity, and the viruses they inhibit vary widely. Recent studies have demonstrated multi...

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Bibliographic Details
Main Authors: Janet E Fulton, Jesus Arango, Rizwana A Ali, Elaine B Bohorquez, Ashlee R Lund, Chris M Ashwell, Petek Settar, Neil P O'Sullivan, Matthew D Koci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4171530?pdf=render