Effects of propofol on colon cancer metastasis through STAT3/HOTAIR axis by activating WIF‐1 and suppressing Wnt pathway

Abstract Background In the present study, we aim to investigate the potential role of propofol in the tumor progression of colon cancer. Methods Human colon cancer cell lines were cultured and exposed with 8 μg/mL propofol. RNA interference was performed to silence the expression of HOTAIR or STAT3...

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Bibliographic Details
Main Authors: Yun‐Fei Zhang, Chang‐Sheng Li, Yi Zhou, Xi‐Hua Lu
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.2840