Berberine Induces p53-Dependent Apoptosis through Inhibition of DNA Methyltransferase3b in Hep3B Cells

The tumor suppressor gene, p53, is inactivated in the human hepatocellular carcinoma cells line, Hep3B. Berberine has been reported to inhibit the proliferation of cancer cells. This study examined whether apoptosis was induced in berberine-treated Hep3B cells and observed the association between ap...

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Bibliographic Details
Main Authors: Dae-Yeon Kim, Seon-Hyoung Kim, Hee-Tae Cheong, Chang-Six Ra, Ki-Jong Rhee, Bae Dong Jung
Format: Article
Language:English
Published: The Korean Society for Clinical Laboratory Science 2020-03-01
Series:Korean Journal of Clinical Laboratory Science
Subjects:
p53