Polytopic vaccination with a live-attenuated dengue vaccine enhances B-cell and T-cell activation, but not neutralizing antibodies

Polytopic vaccination with a live-attenuated dengue vaccine enhances B-cell and T-cell activation, but not neutralizing antibodies

Dengue, caused by dengue viruses (DENVs), is the most common arboviral disease of humans. Several dengue vaccine candidates are at different stages of clinical development and one has been licensed. Inoculation with live-attenuated DENV constructs is an approach that has been used by vaccine develop...

Full description

Bibliographic Details
Main Authors: Taweewun Hunsawong, Sineewanlaya Wichit, Thipwipha Phonpakobsin, Yongyuth Poolpanichupatam, Chonticha Klungthong, Napaporn Latthiwongsakorn, Butsaya Thaisomboonsuk, Rawiwan Im-erbsin, In-Kyu Yoon, Damon W. Ellison, Louis R. Macareo, Anon Srikiatkhachorn, Robert V. Gibbons, Stefan Fernandez
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Heliyon
Subjects:
Vaccine
Virology
Immunology
Health sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S240584401730097X

Internet

http://www.sciencedirect.com/science/article/pii/S240584401730097X

Similar Items