Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney

Critical timing of ACEi initiation prevents compensatory glomerular hypertrophy in the remaining single kidney

Abstract Increasing evidence suggests that single in kidney states (e.g., kidney transplantation and living donation) progressive glomerulosclerosis limits kidney lifespan. Modeling shows that post-nephrectomy compensatory glomerular volume (GV) increase drives podocyte depletion and hypertrophic st...

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Bibliographic Details
Main Authors: Abhijit S. Naik, Su Q. Wang, Mahboob Chowdhury, Jawad Aqeel, Christopher L. O’Connor, Jocelyn E. Wiggins, Markus Bitzer, Roger C. Wiggins
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99124-z

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https://doi.org/10.1038/s41598-021-99124-z

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