Asthma discordance in twins is linked to epigenetic modifications of T cells.

T cells mediate the inflammatory responses observed in asthma among genetically susceptible individuals and have been suspected to be prone to epigenetic regulation. However, these relationships are not well established from past clinical studies that have had limited capacity to control for the eff...

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Bibliographic Details
Main Authors: R Scott Runyon, Leslie M Cachola, Nitya Rajeshuni, Tessa Hunter, Marco Garcia, Regina Ahn, Fred Lurmann, Ruth Krasnow, Lisa M Jack, Rachel L Miller, Gary E Swan, Arunima Kohli, Amanda C Jacobson, Kari C Nadeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511472?pdf=render