Circulating protein fragments of cartilage and connective tissue degradation are diagnostic and prognostic markers of rheumatoid arthritis and ankylosing spondylitis.

Circulating protein fragments of cartilage and connective tissue degradation are diagnostic and prognostic markers of rheumatoid arthritis and ankylosing spondylitis.

Inflammation driven connective tissue turnover is key in rheumatic diseases, such as ankylosing spondylitis (AS). Few biomarkers are available for measuring disease prognosis or the efficacy of interventions applied in these tissue-related conditions. Type II collagen is the primary structural prote...

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Bibliographic Details
Main Authors: Anne C Bay-Jensen, Stephanie Wichuk, Inger Byrjalsen, Diana J Leeming, Nathalie Morency, Claus Christiansen, Morten A Karsdal, Walter P Maksymowych
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554760?pdf=render

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http://europepmc.org/articles/PMC3554760?pdf=render

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