Efficacy of short-course AZT plus 3TC to reduce nevirapine resistance in the prevention of mother-to-child HIV transmission: a randomized clinical trial.

Single-dose nevirapine (sdNVP)-which prevents mother-to-child transmission of HIV-selects non-nucleoside reverse-transcriptase inhibitor (NNRTI) resistance mutations in the majority of women and HIV-infected infants receiving it. This open-label, randomised trial examined the efficacy of short-cours...

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Bibliographic Details
Main Authors: James A McIntyre, Mark Hopley, Daya Moodley, Marie Eklund, Glenda E Gray, David B Hall, Patrick Robinson, Douglas Mayers, Neil A Martinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2760761?pdf=render