Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins

Abstract Background Approximately 15% of human cancers are attributed to viruses. Numerous studies have shown that high-risk human polyomaviruses (HR-HPV) and Merkel cell polyomavirus (MCPyV) are two human tumor viruses associated with anogenetal and oropharyngeal cancers, and with Merkel cell carci...

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Bibliographic Details
Main Authors: Kashif Rasheed, Baldur Sveinbjørnsson, Ugo Moens
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-021-01613-0