Fluorescence-Based Real-Time Analysis of Osteoclast Development

Osteoclasts are multinucleated cells of hematopoietic origin which are critically involved in physiological and pathological bone resorption. They develop from myeloid progenitors through characteristic gene expression changes and intercellular fusion. This process is directed by M-CSF and RANKL whi...

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Bibliographic Details
Main Authors: Áron Pánczél, Simon P. Nagy, János Farkas, Zoltán Jakus, Dávid S. Győri, Attila Mócsai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.657935/full