Targeting Nuclear Factor-kappa B to overcome resistance to chemotherapy.

Targeting Nuclear Factor-kappa B to overcome resistance to chemotherapy.

Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and a major challenge to the treatment of cancer patients, especially those with progressive disease. Chemoresistance is defined by a complex network of factors including multi-drug resistance proteins, reduced cellul...

Full description

Bibliographic Details
Main Authors: Peter eGodwin, Anne-Marie eBaird, Susan eHeavey, Martin eBarr, Kenneth eO'Byrne, Kathy Ann Gately
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Cisplatin
Oncogenes
chemotherapy
NF-κB
Resistance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00120/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00120/full

Similar Items