Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis

Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis

Many synthetically useful reactions are catalyzed by cofactor-dependent enzymes. As cofactors represent a major cost factor, methods for efficient cofactor regeneration are required especially for large-scale synthetic applications. In order to generate a novel and efficient host chassis for bioredu...

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Bibliographic Details
Main Authors: Martina Geier, Christoph Brandner, Gernot A. Strohmeier, Mélanie Hall, Franz S. Hartner, Anton Glieder
Format: Article
Language:English
Published: Beilstein-Institut 2015-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
bioreduction
cofactor regeneration
dihydroxyacetone synthase
methanol utilization pathway
whole-cell biotransformation
Online Access:https://doi.org/10.3762/bjoc.11.190

Internet

https://doi.org/10.3762/bjoc.11.190

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