Hotspots for Initiation of Meiotic Recombination

Homologous chromosomes must pair and recombine to ensure faithful chromosome segregation during meiosis, a specialized type of cell division that occurs in sexually reproducing eukaryotes. Meiotic recombination initiates by programmed induction of DNA double-strand breaks (DSBs) by the conserved typ...

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Bibliographic Details
Main Authors: Andrew J. Tock, Ian R. Henderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Genetics
Subjects:
DSB
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00521/full