Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice

Amyotrophic lateral sclerosis (ALS) is a terminal neurodegenerative disease. Genetic predisposition, epigenetic changes, aging and accumulated life-long environmental exposures are known ALS risk factors. The complex and dynamic interplay between these pathological influences plays a role in disease...

Full description

Bibliographic Details
Main Authors: Claudia Figueroa-Romero, Kai Guo, Benjamin J. Murdock, Ximena Paez-Colasante, Christine M. Bassis, Kristen A. Mikhail, Kristen D. Raue, Matthew C. Evans, Ghislaine F. Taubman, Andrew J. McDermott, Phillipe D. O'Brien, Masha G. Savelieff, Junguk Hur, Eva L. Feldman
Format: Article
Language:English
Published: The Company of Biologists 2020-02-01
Series:Disease Models & Mechanisms
Subjects:
amyotrophic lateral sclerosis
g93a
gut
neurodegeneration
sod1
immunophenotype
Online Access:http://dmm.biologists.org/content/13/2/dmm041947

Internet

http://dmm.biologists.org/content/13/2/dmm041947

Similar Items