Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse.

Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse.

BACKGROUND AND AIMS: Recent studies indicate that hepatitis C virus (HCV) can modulate the expression of various genes including those involved in interferon signaling, and up-regulation of interferon-stimulated genes by HCV was reported to be strongly associated with treatment outcome. To expand ou...

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Bibliographic Details
Main Authors: Masataka Tsuge, Yoshifumi Fujimoto, Nobuhiko Hiraga, Yizhou Zhang, Mayu Ohnishi, Tomohiko Kohno, Hiromi Abe, Daiki Miki, Michio Imamura, Shoichi Takahashi, Hidenori Ochi, C Nelson Hayes, Fuyuki Miya, Tatsuhiko Tsunoda, Kazuaki Chayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3160317?pdf=render

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http://europepmc.org/articles/PMC3160317?pdf=render

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