Losing maleness: Somatic Y chromosome loss at every stage of a man's life

Abstract Mosaic loss of Y chromosome (LOY) is assumed to be among the most common acquired genetic variations in elderly people. Recent studies have linked aging‐related mosaic LOY to the risk of Alzheimer's disease, cancer, and early death. Here, we propose that mosaic LOY can present in men a...

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Bibliographic Details
Main Authors: Mami Miyado, Maki Fukami
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2019-00006