Functional characterization of domains of IPS-1 using an inducible oligomerization system.

Functional characterization of domains of IPS-1 using an inducible oligomerization system.

The innate immune system recognizes viral nucleic acids and stimulates cellular antiviral responses. Intracellular detection of viral RNA is mediated by the Retinoic acid inducible gene (RIG)-I Like Receptor (RLR), leading to production of type I interferon (IFN) and pro-inflammatory cytokines. Once...

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Main Authors: Shiori Takamatsu, Kazuhide Onoguchi, Koji Onomoto, Ryo Narita, Kiyohiro Takahasi, Fumiyoshi Ishidate, Takahiro K Fujiwara, Mitsutoshi Yoneyama, Hiroki Kato, Takashi Fujita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23308256/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23308256/?tool=EBI

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