Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson's Disease.

In Parkinson's disease (PD), alpha-synuclein (a-syn) can be detected in biological fluids including saliva. Although previous studies found reduced a-syn total (a-syntotal) concentration in saliva of PD patients, no studies have previously examined salivary a-syn oligomers (a-synolig) concentra...

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Bibliographic Details
Main Authors: Giorgio Vivacqua, Anna Latorre, Antonio Suppa, Michela Nardi, Sara Pietracupa, Romina Mancinelli, Giovanni Fabbrini, Carlo Colosimo, Eugenio Gaudio, Alfredo Berardelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807094?pdf=render