Rewards of divergence in sequences, 3-D structures and dynamics of yeast and human spliceosome SF3b complexes

The evolution of homologous and functionally equivalent multiprotein assemblies is intriguing considering sequence divergence of constituent proteins. Here, we studied the implications of protein sequence divergence on the structure, dynamics and function of homologous yeast and human SF3b spliceoso...

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Bibliographic Details
Main Authors: Arangasamy Yazhini, Sankaran Sandhya, Narayanaswamy Srinivasan
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Structural Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X2100009X