Targeting DNA Methyltranferases in Urological Tumors

Targeting DNA Methyltranferases in Urological Tumors

Urological cancers are a heterogeneous group of malignancies accounting for a considerable proportion of cancer-related morbidity and mortality worldwide. Aberrant epigenetic traits, especially altered DNA methylation patterns constitute a hallmark of these tumors. Nonetheless, these alterations are...

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Bibliographic Details
Main Authors: Ângela Marques-Magalhães, Inês Graça, Rui Henrique, Carmen Jerónimo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
bladder cancer
kidney cancer
prostate cancer
testicular cancer
DNA methylgtransferases inhibitors
pre-clinical studies
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00366/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00366/full

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