Lipids and lipoxidation in human brain aging. Mitochondrial ATP-synthase as a key lipoxidation target

The human brain is a target of the aging process like other cell systems of the human body. Specific regions of the human brain exhibit differential vulnerabilities to the aging process. Yet the underlying mechanisms that sustain the preservation or deterioration of neurons and cerebral functions ar...

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Bibliographic Details
Main Authors: Mariona Jové, Irene Pradas, Mayelin Dominguez-Gonzalez, Isidro Ferrer, Reinald Pamplona
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718309613