Simultaneous quantification of natural and inducible regulatory T-cell subsets during interferon-β therapy of multiple sclerosis patients

Simultaneous quantification of natural and inducible regulatory T-cell subsets during interferon-β therapy of multiple sclerosis patients

Abstract Background The mechanisms underlying the therapeutic activity of interferon-β in multiple sclerosis are still not completely understood. In the present study, we evaluated the short and long-term effects of interferon-β treatment on different subsets of regulatory T cells in relapsing–remit...

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Bibliographic Details
Main Authors: Marco Chiarini, Ruggero Capra, Federico Serana, Diego Bertoli, Alessandra Sottini, Viviana Giustini, Cristina Scarpazza, Marco Rovaris, Valentina Torri Clerici, Diana Ferraro, Simonetta Galgani, Claudio Solaro, Marta Zaffira Conti, Andrea Visconti, Luisa Imberti, SURROGATE Study Group
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Translational Medicine
Subjects:
Multiple sclerosis
Interferon-β
Regulatory T cells
Treg subsets
Online Access:http://link.springer.com/article/10.1186/s12967-020-02329-5

Internet

http://link.springer.com/article/10.1186/s12967-020-02329-5

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