Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

Abstract Human microbiota-associated (HMA) mice are an important model to study the relationship between liver diseases and intestinal microbiota. We describe a new method to humanize conventional mice based on bowel cleansing with polyethylene glycol followed by fecal microbiota transplantation (FM...

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Bibliographic Details
Main Authors: Laura Wrzosek, Dragos Ciocan, Patrick Borentain, Madeleine Spatz, Virginie Puchois, Cindy Hugot, Gladys Ferrere, Camille Mayeur, Gabriel Perlemuter, Anne-Marie Cassard
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25300-3