Participation of ATP7A in macrophage mediated oxidation of LDL
ATP7A primarily functions to egress copper from cells, thereby supplying this cofactor to secreted copper-accepting enzymes. This ATPase has attracted significant attention since the discovery of its mutation leading to human Menkes disease and the demonstration of its distribution in various tissue...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-06-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520410211 |