Noumeavirus replication relies on a transient remote control of the host nucleus

Large dsDNA viruses either replicate in or disrupt the nucleus to gain access to host RNA polymerases, or they rely on virus-encoded, packaged RNA polymerases. Here, the authors show that Noumeavirus replicates in the cytoplasm and relies on a transient recruitment of nuclear proteins to initiate re...

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Bibliographic Details
Main Authors: Elisabeth Fabre, Sandra Jeudy, Sébastien Santini, Matthieu Legendre, Mathieu Trauchessec, Yohann Couté, Jean-Michel Claverie, Chantal Abergel
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15087