Animal Models of Dengue Virus Infection

The development of animal models of dengue virus (DENV) infection and disease has been challenging, as epidemic DENV does not naturally infect non-human species. Non-human primates (NHPs) can sustain viral replication in relevant cell types and develop a robust immune response, but they do not devel...

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Bibliographic Details
Main Authors: Eva Harris, Simona Zompi
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/4/1/62/