Mining for viral fragments in methylation enriched sequencing data

Mining for viral fragments in methylation enriched sequencing data

Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain (MBD) affinity purification based sequencing is often used for DNA-methylation profiling, but up to 30% of the sequenced fragments cannot be mapped uniq...

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Bibliographic Details
Main Authors: Klaas eMensaert, Wim eVan Criekinge, Olivier eThas, Ed eSchuuring, Renske D. M. Steenbergen, G. Bea A. Wisman, Tim eDe Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Genetics
Subjects:
Epigenomics
Viruses
bioinformatics
Human papillomavirus
cervical cancer
next generation sequencing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00016/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00016/full

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