Prognostic Significance of Immune Checkpoints HLA-G/ILT-2/4 and PD-L1 in Colorectal Cancer

Immune checkpoint inhibitors (ICIs) have become a promising area of research for cancer treatment. In addition to the well-known ICIs targeting PD-1/PD-L1, HLA-G/ILT-2/-4 is relatively new immune checkpoint that has been evaluated in early clinical trials in patients with advanced solid tumors. In t...

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Bibliographic Details
Main Authors: Qiong-Yuan Chen, Yu-Xin Chen, Qiu-Yue Han, Jiang-Gang Zhang, Wen-Jun Zhou, Xia Zhang, Yao-Han Ye, Wei-Hua Yan, Aifen Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.679090/full