The in-vivo use of superparamagnetic iron oxide nanoparticles to detect inflammation elicits a cytokine response but does not aggravate experimental arthritis.

Superparamagnetic Iron Oxide Nanoparticles (SPION) are used in diagnostic imaging of a variety of different diseases. For such in-vivo application, an additional coating with a polymer, for example polyvinyl alcohol (PVA), is needed to stabilize the SPION and prevent aggregation. As the particles ar...

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Bibliographic Details
Main Authors: Eline A Vermeij, Marije I Koenders, Miranda B Bennink, Lindsey A Crowe, Lionel Maurizi, Jean-Paul Vallée, Heinrich Hofmann, Wim B van den Berg, Peter L E M van Lent, Fons A J van de Loo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425489?pdf=render