Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly

The regulation of mitochondrial RNA processing and its importance for ribosome biogenesis and energy metabolism are not clear. We generated conditional knockout mice of the endoribonuclease component of the RNase P complex, MRPP3, and report that it is essential for life and that heart and skeletal-...

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Bibliographic Details
Main Authors: Oliver Rackham, Jakob D. Busch, Stanka Matic, Stefan J. Siira, Irina Kuznetsova, Ilian Atanassov, Judith A. Ermer, Anne-Marie J. Shearwood, Tara R. Richman, James B. Stewart, Arnaud Mourier, Dusanka Milenkovic, Nils-Göran Larsson, Aleksandra Filipovska
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Subjects:
RNA metabolism
mitochondria
PPR domains
RNA-seq
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309494

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http://www.sciencedirect.com/science/article/pii/S2211124716309494

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